听力与言语-语言病理学

行为科学

医学伦理学

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  • Covert orienting of attention in macaques. I. Effects of behavioral context.

    abstract::1. A task was used by Posner (1980) to measure shifts of attention that occurred covertly, in the absence of an eye movement or other orienting response. This paradigm was used here to assess the nature of covert attentional orienting in monkeys to develop an animal model for neurophysiological studies. Shifts of atte...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.70.1.431

    authors: Bowman EM,Brown VJ,Kertzman C,Schwarz U,Robinson DL

    更新日期:1993-07-01 00:00:00

  • Synaptic excitation of alpha-motoneurons by dorsal root afferents in the neonatal rat spinal cord.

    abstract::1. Excitatory synaptic transmission in mono- and polysynaptic pathways between dorsal root afferents and alpha-motoneurons was studied in the spinal cord preparation of the neonatal rat isolated in vitro, using sharp-electrode intracellular recordings. 2. The duration of monosynaptic excitatory postsynaptic potentials...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.70.1.406

    authors: Pinco M,Lev-Tov A

    更新日期:1993-07-01 00:00:00

  • The actions of hydrogen sulfide on dorsal raphe serotonergic neurons in vitro.

    abstract::1. The actions of hydrogen sulfide (HS-) on membrane and synaptic properties of dorsal raphe (DR) serotonergic cells were studied in the in vitro brain stem slice preparation, using intracellular sharp microelectrode and whole-cell recording techniques. 2. Sulfide produced two reversible, concentration-dependent effec...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.70.1.81

    authors: Kombian SB,Reiffenstein RJ,Colmers WF

    更新日期:1993-07-01 00:00:00

  • Plateau pattern of afferent discharge rate from frog muscle spindles.

    abstract::1. A characteristic plateau pattern was observed in the rate of afferent discharges during ramp-and-hold stretch of spindles isolated from semitendinosus muscles of frogs. The plateau pattern was more frequent in summer frogs (84%) than winter frogs (11%). 2. The plateau pattern consisted of a discharge rate around 12...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.70.1.275

    authors: Sokabe M,Nunogaki K,Naruse K,Soga H,Fujitsuka N,Yoshimura A,Ito F

    更新日期:1993-07-01 00:00:00

  • Otolith-brain stem connectivity: evidence for differential neural activation by vestibular hair cells based on quantification of FOS expression in unilateral labyrinthectomized rats.

    abstract::1. The effects of acute and chronic labyrinthectomies on Fos-defined neuronal activity induced by rotation were determined with the use of quantitative image analysis procedures. Unilateral sodium arsanilate labyrinthectomies (UL) were performed either 24 h (acute) or 2 wk (chronic) before exposure to a 90 min, 2-G ce...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.70.1.117

    authors: Kaufman GD,Anderson JH,Beitz AJ

    更新日期:1993-07-01 00:00:00

  • Position-specific adaptation in complex cell receptive fields of the cat striate cortex.

    abstract::1. Responses of complex cells in cat striate cortex were studied with flashed light slit stimuli. The responses to slits flashed in different positions in the receptive field were assessed quantitatively before and after periods of prolonged stimulation of one small region of the receptive field. This type of prolonge...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.6.2209

    authors: Marlin S,Douglas R,Cynader M

    更新日期:1993-06-01 00:00:00

  • Dynamics of reflex cocontraction in hermit crab abdomen: experiments and a systems model.

    abstract::1. Both stretch and release of the ventral superficial muscles (VSM) in the abdomen of the hermit crab, Pagurus pollicarus, activate the VSM motoneurons in the intact animal and in the isolated abdomen. 2. This reflex was studied by recording intracellularly from muscle fibers innervated by single motoneurons during s...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.6.1904

    authors: Chapple WD

    更新日期:1993-06-01 00:00:00

  • Effects of soma isolation on outward currents measured under voltage clamp in spiny lobster stomatogastric motor neurons.

    abstract::1. Outward currents in identified cell types from the pyloric system of the stomatogastric ganglion (STG) of the spiny lobster, Panulirus marginatus, were studied under two-microelectrode voltage clamp. A comparison was made between data from intact cells and somata isolated by ligation of the primary neurite of these...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.6.2056

    authors: Hartline DK,Gassie DV,Jones BR

    更新日期:1993-06-01 00:00:00

  • Local anesthetics block transient outward potassium currents in rat neocortical neurons.

    abstract::1. Whole-cell patch clamp techniques were used to record transient outward potassium currents in embryonic rat neocortical neurons maintained in culture. The effect of lidocaine and its quaternary derivative QX222 on this transient outward current (TOC) was examined. 2. Extracellular application of lidocaine produced ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.6.1966

    authors: Andreasen M,Hablitz JJ

    更新日期:1993-06-01 00:00:00

  • Timing of medullary late-inspiratory neuron discharges: vagal afferent effects indicate possible off-switch function.

    abstract::1. In decerebrate paralyzed cats, we observed the responses of ventral and dorsal medullary inspiratory (I) neurons to two types of vagal afferent input that shorten neural I: lung inflation and vagal electrical stimulation. 2. A study population of 15 I neurons whose firing patterns suggested involvement in the inspi...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.5.1784

    authors: Cohen MI,Huang WX,Barnhardt R,See WR

    更新日期:1993-05-01 00:00:00

  • Static and dynamic responses of periodontal ligament mechanoreceptors and intradental mechanoreceptors.

    abstract::1. The response properties of 39 periodontal ligament mechanoreceptors (PDLMs) and 12 intradental mechanoreceptors (IMs) related to the intact mandibular canine tooth were isolated by extracellular recording methods from the ipsilateral trigeminal semilunar ganglion. 2. The stimulus threshold and response magnitude of...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.5.1567

    authors: Dong WK,Shiwaku T,Kawakami Y,Chudler EH

    更新日期:1993-05-01 00:00:00

  • Interaction and synchronization between two abdominal motor systems in crayfish.

    abstract::1. Extracellular and intracellular recordings from an isolated thoraco-abdominal preparation of the crayfish, Pacifastacus leniusculus, demonstrate that the swimmeret and the abdominal positioning systems can at times be spontaneously coordinated with each other. 2. Two forms of coordination were encountered between t...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.5.1373

    authors: Chrachri A,Neil DM

    更新日期:1993-05-01 00:00:00

  • Nucleus Z: a somatosensory relay to motor thalamus.

    abstract::1. It was the aim of this study to show that nucleus Z of the cat medulla acts as a relay between the spinal cord and the ventral lateral (VL) nucleus of the motor thalamus. For this purpose, extracellular recordings were made from neurons that were antidromically identified by stimulation in the rostral thalamus, par...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.5.1607

    authors: Mackel R,Miyashita E

    更新日期:1993-05-01 00:00:00

  • A cortical EEG frequency with a REM-specific increase in amplitude.

    abstract::1. We used period/amplitude (PA) analysis to survey electroencephalography (EEG) across vigilance states in the Sprague-Dawley rat. We found a fast cortical EEG frequency band, which we designate rho, whose wave amplitude in rapid eye movement (REM) was elevated above the levels in both waking and nonrapid eye movemen...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.4.1368

    authors: Campbell IG,Feinberg I

    更新日期:1993-04-01 00:00:00

  • Human flexor reflex modulation during cycling.

    abstract::1. Human flexor reflex (HFR) responses were elicited during ergometer cycling in neurologically intact humans with the objective of understanding the influence of lower limb muscle activity on phase-dependent reflex modulation during movement. The experimental setup permitted control over background muscle activity an...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.4.1212

    authors: Brown DA,Kukulka CG

    更新日期:1993-04-01 00:00:00

  • Barbiturate depresses simple spike activity of cerebellar Purkinje cells after climbing fiber input.

    abstract::1. Some scientists reported that the simple spike (SS) activity was transiently depressed after climbing fiber input, but others reported that predominant population of Purkinje cells increased their SS activity after the complex spike (CS). In the present study, SS activity after spontaneous CS was compared before an...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.4.1082

    authors: Sato Y,Miura A,Fushiki H,Kawasaki T

    更新日期:1993-04-01 00:00:00

  • Effects of low-frequency stimulation of the superior colliculus on spontaneous and visually guided saccades.

    abstract::1. The first experiment of this study determined the effects of low-frequency stimulation of the monkey superior colliculus on spontaneous saccades in the dark. Stimulation trains, subthreshold for eliciting short-latency fixed-vector saccades, were highly effective at biasing the metrics (direction and amplitude) of ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.3.953

    authors: Glimcher PW,Sparks DL

    更新日期:1993-03-01 00:00:00

  • Potassium channel family in giant motor axons of Aglantha digitale.

    abstract::1. The simplicity of the jellyfish nervous system makes it an ideal preparation to assess the contributions of different ion channels to behavior. In the giant motor axons of the jellyfish Aglantha digitale, low-threshold spikes elicit slow swimming, whereas escape swimming depends on a higher-threshold, overshooting ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.3.894

    authors: Meech RW,Mackie GO

    更新日期:1993-03-01 00:00:00

  • Wide dynamic range but not nociceptive-specific neurons encode multidimensional features of prolonged repetitive heat pain.

    abstract::1. To better characterize temporal and spatial mechanisms involved in the coding of prolonged nociceptive stimuli in the spinal cord, the responses of dorsal horn wide dynamic range (WDR) and nociceptive-specific (NS) neurons to prolonged, repetitive noxious heat stimuli (45-49 degrees C) were examined in unanesthetiz...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.3.703

    authors: Coghill RC,Mayer DJ,Price DD

    更新日期:1993-03-01 00:00:00

  • A molecularly defined cardiorespiratory interneuron expressing SDPFLRFamide/GDPFLRFamide in the snail Lymnaea: monosynaptic connections and pharmacology.

    abstract::1. Neuron-specific expression of alternately spliced exons of the gene encoding the Phe-Met-Arg-Phe-NH2 (FMRFamide) family of neuropeptides and the role of encoded peptides in synaptic transmission were examined in an identified cardiorespiratory interneuron, the visceral white interneuron (VWI), in the snail Lymnaea....

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.3.915

    authors: Skingsley DR,Bright K,Santama N,van Minnen J,Brierley MJ,Burke JF,Benjamin PR

    更新日期:1993-03-01 00:00:00

  • Properties of synaptic transmission from photoreceptors to bipolar cells in the mudpuppy retina.

    abstract::1. Simultaneous, whole-cell recordings were obtained from synaptically coupled photoreceptor/bipolar cell pairs, by the use of direct visualization in a superfused, mudpuppy retinal slice preparation. 2. OFF-bipolar cells (BPs) generated sign-conserving responses when extrinsic current was injected into rods and cones...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.2.352

    authors: Kim HG,Miller RF

    更新日期:1993-02-01 00:00:00

  • Cholinergic modulation of synaptic inhibition in the guinea pig hippocampus in vitro: excitation of GABAergic interneurons and inhibition of GABA-release.

    abstract::1. The effect of cholinergic receptor activation on gamma-aminobutyric acid (GABA)-mediated inhibitory synaptic transmission was investigated in voltage-clamped CA1 pyramidal neurons (HPNs) in the guinea pig hippocampal slice preparation. 2. The cholinergic agonist carbachol (1-10 microM) induced a prominent and susta...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.2.626

    authors: Behrends JC,ten Bruggencate G

    更新日期:1993-02-01 00:00:00

  • Gustatory neural coding in the monkey cortex: the quality of sweetness.

    abstract::1. We analyzed the activity of single neurons in gustatory cortex of alert cynomolgus monkeys in response to the four basic taste stimuli and to a range of chemicals, all of which are predominantly sweet to humans. 2. We recorded taste-evoked responses from a cortical area that measured 4.0 mm in its anteroposterior e...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.2.482

    authors: Plata-Salamán CR,Scott TR,Smith-Swintosky VL

    更新日期:1993-02-01 00:00:00

  • Neural circuit tuning fly visual interneurons to motion of small objects. I. Dissection of the circuit by pharmacological and photoinactivation techniques.

    abstract::1. Visual interneurons tuned to the motion of small objects are found in many animal species and are assumed to be the neuronal basis of figure-ground discrimination by relative motion. A well-examined example is the FD1-cell in the third visual neuropil of blowflies. This cell type responds best to motion of small ob...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.2.329

    authors: Warzecha AK,Egelhaaf M,Borst A

    更新日期:1993-02-01 00:00:00

  • Premotor cortex of monkeys: set- and movement-related activity reflecting amplitude and direction of wrist movements.

    abstract::1. Neuronal activity was recorded from the premotor cortex (PM) of Japanese monkeys while they performed hand movements with different amplitudes and directions. On each behavioral trial, two instructions were given sequentially: 1) an amplitude instruction (large or small) and 2) a direction instruction (flexion or e...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.1.187

    authors: Kurata K

    更新日期:1993-01-01 00:00:00

  • The postsynaptic induction of nonassociative long-term depression of excitatory synaptic transmission in rat hippocampal slices.

    abstract::1. Long-term depression (LTD) is an activity-dependent reduction in the strength of synaptic transmission that can persist for hours. It is a neural model for processes underlying learning and memory, such as extinction and forgetting. LTD of excitatory postsynaptic potentials (EPSPs) in cells of the CA1 region of hip...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.1.219

    authors: Christofi G,Nowicky AV,Bolsover SR,Bindman LJ

    更新日期:1993-01-01 00:00:00

  • Postnatal development of a persistent Na+ current in pyramidal neurons from rat sensorimotor cortex.

    abstract::1. Whole-cell recordings were performed on acutely isolated pyramidal neurons from rat sensorimotor cortex 2 to 21 days postnatal to study the expression of a tetrodotoxin (TTX) sensitive, voltage dependent, persistent Na+ current (INaP) during different stages of postnatal development. 2. INaP was activated positive ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1993.69.1.290

    authors: Alzheimer C,Schwindt PC,Crill WE

    更新日期:1993-01-01 00:00:00

  • Responses of spinothalamic tract neurons to mechanical and thermal stimuli in an experimental model of peripheral neuropathy in primates.

    abstract::1. An experimental peripheral neuropathy (EPN) was induced in three monkeys (Macaca fascicularis) by ligation of spinal nerve L7. Behavioral responses to innocuous mechanical stimuli were tested before and after the surgery. Two weeks after the nerve ligation, the activity of spinothalamic tract (STT) neurons was reco...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.68.6.1951

    authors: Palecek J,Dougherty PM,Kim SH,Palecková V,Lekan H,Chung JM,Carlton SM,Willis WD

    更新日期:1992-12-01 00:00:00

  • A long closed state of the synaptosomal bursting potassium channel confers a statistical memory.

    abstract::1. The statistical properties of the bursting potassium channel from fused Torpedo synaptosomes were studied by using patch-clamp recording and time series analysis. 2. Voltage steps produce channel openings; the number of channels opening fluctuates from trial to trial. The maximal current observed in each trial is s...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.68.6.2260

    authors: Rahamimoff R,Edry-Schiller J,Ginsburg S

    更新日期:1992-12-01 00:00:00

  • Nimodipine increases excitability of rabbit CA1 pyramidal neurons in an age- and concentration-dependent manner.

    abstract::1. Cellular properties were studied before and after bath application of the dihydropyridine L-type calcium channel antagonist nimodipine in aging and young rabbit hippocampal CA1 pyramidal cells in vitro. Various concentrations of nimodipine, ranging from 10 nM to 10 microM, were tested to investigate age- and concen...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.68.6.2100

    authors: Moyer JR Jr,Thompson LT,Black JP,Disterhoft JF

    更新日期:1992-12-01 00:00:00

  • Primary motor cortical activity related to the weight and texture of grasped objects in the monkey.

    abstract::1. Two monkeys were trained to grasp an object between the thumb and index finger and lift it to a vertical distance of 12-25 mm. Up to 12 different conditions defined by different combinations of object weights (15, 65, and 115 g) and four surface textures (oiled metal, smooth metal, fine and coarse sandpaper) were u...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.68.5.1867

    authors: Picard N,Smith AM

    更新日期:1992-11-01 00:00:00

  • Transient K current in the somatic membrane of cultured central neurons of embryonic rat.

    abstract::1. Somatic K currents of cultured hippocampal, striatal, and spinal cord neurons of embryonic rat were recorded under voltage clamp in membrane spheres ("blebs") excised by means of a tight-seal pipette. 2. The somatic K current in blebs was subject to rapid and near complete inactivation during 300-ms depolarizations...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.68.5.1708

    authors: Rizzo MA,Nonner W

    更新日期:1992-11-01 00:00:00

  • Oscillatory discharge in the visual system: does it have a functional role?

    abstract::1. The discharge of individual neurons in the visual cortex and lateral geniculate nucleus (LGN) of anesthetized and paralyzed cats and kittens was examined for the presence of oscillatory activity. Neural firing was evoked through the monoptic or dichoptic presentation of drifting gratings and random sequences of fla...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.68.5.1558

    authors: Ghose GM,Freeman RD

    更新日期:1992-11-01 00:00:00

  • Functional properties and axon terminations of interneurons in laminae III-V of the mammalian spinal dorsal horn in vitro.

    abstract::1. The functional organization of interneurons in spinal laminae III-V was studied in an isolated preparation of hamster dorsal horn with sensory innervation from an excised skin patch. Morphological details of 40 neurons were visualized by intracellular injection of horseradish peroxidase. Active and passive membrane...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.68.5.1746

    authors: Schneider SP

    更新日期:1992-11-01 00:00:00

  • Electrotonic length estimates in neurons with dendritic tapering or somatic shunt.

    abstract::1. Compartmental models were used to compute the time constants and coefficients of voltage and current transients in hypothetical neurons having tapering dendrites or soma shunt and in a serially reconstructed motoneuron with soma shunt. These time constants and coefficients were used in equivalent cylinder formulas ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.68.4.1421

    authors: Holmes WR,Rall W

    更新日期:1992-10-01 00:00:00

  • Ca(2+)-independent and Ca(2+)-dependent stimulation of quantal neurosecretion in avian ciliary ganglion neurons.

    abstract::1. Although it is generally agreed that Ca2+ couples depolarization to the release of neurotransmitters, hypertonic saline and ethanol (ETOH) evoke neurosecretion independent of extracellular Ca2+. One possible explanation is that these agents release Ca2+ from an intracellular store that then stimulates Ca(2+)-depend...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.68.4.1229

    authors: Brosius DC,Hackett JT,Tuttle JB

    更新日期:1992-10-01 00:00:00

  • Two-tone suppression in the basilar membrane of the cochlea: mechanical basis of auditory-nerve rate suppression.

    abstract::1. The vibratory response to two-tone stimuli was measured in the basilar membrane of the chinchilla cochlea by means of the Mössbauer technique or laser velocimetry. Measurements were made at sites with characteristic frequency (CF, the frequency at which an auditory structure is most sensitive) of 7-10 kHz, located ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.68.4.1087

    authors: Ruggero MA,Robles L,Rich NC

    更新日期:1992-10-01 00:00:00

  • Activity-induced elevations of intracellular calcium concentration in pyramidal and nonpyramidal cells of the CA3 region of rat hippocampal slice cultures.

    abstract::1. Depolarization-induced elevations of intracellular calcium concentration ([Ca2+]i) were examined in slice-cultured hippocampal pyramidal and nonpyramidal cells of the CA3 region by combined intracellular and multisite fura-2 recording techniques. 2. In pyramidal cells, spiking activity induced by depolarizing curre...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.68.3.961

    authors: Knöpfel T,Gähwiler BH

    更新日期:1992-09-01 00:00:00

  • Responses of neurons in the gracile nucleus of cats to innocuous and noxious stimuli: basic characterization and antidromic activation from the thalamus.

    abstract::1. Responses to innocuous and noxious mechanical and thermal stimuli were recorded from 90 neurons in the gracile nucleus of anesthetized cats. Cells were tested by antidromic activation for projections to the contralateral ventrobasal thalamus. 2. Cells were characterized broadly by their responses to mechanical stim...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.68.3.818

    authors: Cliffer KD,Hasegawa T,Willis WD

    更新日期:1992-09-01 00:00:00

  • A motor area rostral to the supplementary motor area (presupplementary motor area) in the monkey: neuronal activity during a learned motor task.

    abstract::1. The rostromesial agranular frontal cortex of macaque monkey (Macaca fuscata), traditionally defined as the supplementary motor area (SMA), was studied using various physiological techniques to delineate two different areas rostrocaudally. 2. Field and unitary responses to electrical stimulation of the primary motor...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1992.68.3.653

    authors: Matsuzaka Y,Aizawa H,Tanji J

    更新日期:1992-09-01 00:00:00

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